The Prevalence of Transient and Permanent Congenital Hypothyroidism in Infants of Kurdistan Province, Iran (2006-2014)

Authors

  • Alireza Alikhani Deputy of Medical Education Development Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
  • Behzad Gholamaliee Msc in Health Education, Hamadan University of Medical Sciences, Hamadan, Iran.
  • Ebrahim Ghaderi Social Determinants of Health Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran.
  • Elham Goodarzi Social Determinants of Health Research Centre, Medical School, Rafsanjan University of Medical Science, Rafsanjan, Iran.
  • Erfan Ayubi PhD Candidate of Epidemiology, Department of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Kamyar Mansori Social Development and Health Promotion Research Center, Gonabad University of Medical Sciences, Gonabad, Iran.
  • Nahid Ghotbi Associate Professor, Cellular & Molecular Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran.
  • Reza Beiranvand MSc Department of Health and Community Medicine, Faculty of Medicine, Dezful University of Medical Sciences, Dezful, Iran.
  • Saeeid Ghavi Social Determinants of Health Research Center, Department of Public Health, Birjand University of Medical Sciences, Birjand, Iran.
  • Sairan Nili PhD Student of Epidemiology, Kerman University of Medical Sciences, Kerman, Iran.
  • Salman Khazaei Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
  • Zaher khazaei Social Determinants of Health Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Abstract:

Background: Congenital hypothyroidism (CH) is the most common endocrine diseases and one of the major causes of preventable mental retardation. This study was conducted to investigate the prevalence of transient and permanent congenital hypothyroidism in Kurdistan province, Iran.Materials and Methods: In this cross-sectional study, all registered congenital hypothyroidism neonate of health centers of cities covered by Kurdistan University of Medical Sciences during 2006 to 2014 entered to study. Demographic and laboratory information of CH neonates was collected and entered into the Stata-12 and was analyzed using student t-test and Chi-square statistic and P- value less than 0.05 was considered.Results: Overall incidence rate during 2006 to 2014 for province was 1.8, 2.3, 3.2, 4.3, 3.3, 4.0, 3.6, 4.6 and 2.7, respectively per 1000 neonates in this period. The number of diagnosed patients was 855 cases including 519 (60.7%) boys and 336 (39.3%) girls who 516 (60.4%) cases were from urban areas. Of the total patients, 202 (22.6%) were permanent. There was no significant difference between gender, location, type of childbirth, and season of birth with transient and permanent types of disease (P˃0.05); while, there was a significant statistical relationship between consanguineous marriages and congenital hypothyroidism (P

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Journal title

volume 5  issue 2

pages  4309- 4318

publication date 2017-02-01

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